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Table 3 Impact of creatinine excretion

From: Adequacy of decision-making based on each kidney function estimation method for Japanese living kidney donor candidates: a retrospective observational study

 

Total

Low Cr excretion

High Cr excretion

P

n

210

105

105

 

Male (%)

126 (60%)

41 (39%)

85 (81%)

< 0.01

Age

52.5 (16–85)

57 (16–85)

47 (17–77)

< 0.01

BSA (m2)

1.63 (1.20–2.20)

1.52 (1.20–2.13)

1.73 (1.46–2.20)

< 0.01

U-Cr (mg/day)

1025 (413–2012)

843 (413–1019)

1260 (1031–2012)

< 0.01

Cr (mg/dL)

1.13 (0.45–6.31)

1.00 (0.45–6.31)

0.80 (0.45–2.62)

n.s.

Cys (mg/L)

1.24 (0.52–5.67)

1.27 (0.60–5.67)

0.98 (0.52–2.37)

n.s.

CIn (mL/min/1.73 m2)

55.5 (6.0–147.0)

49.0 (6.0–147.0)

61.0 (19.0–147.0)

< 0.01

CCr (mL/min/1.73 m2)

68.0 (8.5–167.3)

57.5 (8.5–167.3)

75.7 (24.1–158.7)

< 0.01

eGFRCr (mL/min/1.73 m2)

51.0 (7.9–144.4)

48.2 (7.9–144.4)

55.0 (16.2–138.1)

n.s.

eGFRCys (mL/min/1.73 m2)

60.0 (5.7–181.2)

53.0 (5.7–142.0)

62.1 (13.2–181.2)

< 0.05

eGFRCr+Cys (mL/min/1.73 m2)

54.8 (7.3–153.1)

51.6 (7.3–143.2)

59.9 (14.7–153.1)

n.s.

eGFR-CKDEPICr (mL/min/1.73 m2)

57.7 (7.1–118.4)

54.1 (7.1–118.4)

61.3 (15.1–116.1)

n.s.

CCr-CIn (mL/min/1.73 m2)

10.6 (− 50.5–78.4)

8.5 (− 50.5–78.4)

12.6 (− 23.4–71.8)

n.s.

eGFRCr-CIn (mL/min/1.73 m2)

− 5.0 (− 56.2–41.4)

0.3 (− 42.4–40.3)

− 10.0 (− 56.2–41.4)

< 0.01

eGFRCys-CIn (mL/min/1.73 m2)

3.0 (− 51.0–57.5)

2.9 (− 51.0–57.5)

4.2 (− 32.1–56.3)

n.s.

eGFRCr+Cys-CIn (mL/min/1.73 m2)

− 0.6 (− 41.1–48.9)

0.4 (− 41.1–44.2)

− 1.7 (− 40.5–48.9)

n.s.

eGFR-CKDEPICr-CIn (mL/min/1.73 m2)

− 2.4 (− 46.8–47.4)

− 0.4 (− 44.6–44.6)

− 7.0 (− 46.8–47.4)

< 0.01

  1. Continuous variables were presented as medians and ranges (minimum–maximum). Mann-Whitney U test was used to compare between groups. Categorized variables were presented as percentages and chi-squared tests were used to detect between-group difference. GFR glomerular filtration rate; eGFR estimated GFR based on Cr (creatinine) Cys (cystatin C), Cr + Cys (an average of Cr + Cys), or CKDEPICr (a Cr-based equation from The Chronic Kidney Disease Epidemiology Collaboration ([CKD-EPI]); CIn inulin clearance; CCr creatinine clearance; n.s. no significance