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Table 3 Impact of creatinine excretion

From: Adequacy of decision-making based on each kidney function estimation method for Japanese living kidney donor candidates: a retrospective observational study

 TotalLow Cr excretionHigh Cr excretionP
n210105105 
Male (%)126 (60%)41 (39%)85 (81%)< 0.01
Age52.5 (16–85)57 (16–85)47 (17–77)< 0.01
BSA (m2)1.63 (1.20–2.20)1.52 (1.20–2.13)1.73 (1.46–2.20)< 0.01
U-Cr (mg/day)1025 (413–2012)843 (413–1019)1260 (1031–2012)< 0.01
Cr (mg/dL)1.13 (0.45–6.31)1.00 (0.45–6.31)0.80 (0.45–2.62)n.s.
Cys (mg/L)1.24 (0.52–5.67)1.27 (0.60–5.67)0.98 (0.52–2.37)n.s.
CIn (mL/min/1.73 m2)55.5 (6.0–147.0)49.0 (6.0–147.0)61.0 (19.0–147.0)< 0.01
CCr (mL/min/1.73 m2)68.0 (8.5–167.3)57.5 (8.5–167.3)75.7 (24.1–158.7)< 0.01
eGFRCr (mL/min/1.73 m2)51.0 (7.9–144.4)48.2 (7.9–144.4)55.0 (16.2–138.1)n.s.
eGFRCys (mL/min/1.73 m2)60.0 (5.7–181.2)53.0 (5.7–142.0)62.1 (13.2–181.2)< 0.05
eGFRCr+Cys (mL/min/1.73 m2)54.8 (7.3–153.1)51.6 (7.3–143.2)59.9 (14.7–153.1)n.s.
eGFR-CKDEPICr (mL/min/1.73 m2)57.7 (7.1–118.4)54.1 (7.1–118.4)61.3 (15.1–116.1)n.s.
CCr-CIn (mL/min/1.73 m2)10.6 (− 50.5–78.4)8.5 (− 50.5–78.4)12.6 (− 23.4–71.8)n.s.
eGFRCr-CIn (mL/min/1.73 m2)− 5.0 (− 56.2–41.4)0.3 (− 42.4–40.3)− 10.0 (− 56.2–41.4)< 0.01
eGFRCys-CIn (mL/min/1.73 m2)3.0 (− 51.0–57.5)2.9 (− 51.0–57.5)4.2 (− 32.1–56.3)n.s.
eGFRCr+Cys-CIn (mL/min/1.73 m2)− 0.6 (− 41.1–48.9)0.4 (− 41.1–44.2)− 1.7 (− 40.5–48.9)n.s.
eGFR-CKDEPICr-CIn (mL/min/1.73 m2)− 2.4 (− 46.8–47.4)− 0.4 (− 44.6–44.6)− 7.0 (− 46.8–47.4)< 0.01
  1. Continuous variables were presented as medians and ranges (minimum–maximum). Mann-Whitney U test was used to compare between groups. Categorized variables were presented as percentages and chi-squared tests were used to detect between-group difference. GFR glomerular filtration rate; eGFR estimated GFR based on Cr (creatinine) Cys (cystatin C), Cr + Cys (an average of Cr + Cys), or CKDEPICr (a Cr-based equation from The Chronic Kidney Disease Epidemiology Collaboration ([CKD-EPI]); CIn inulin clearance; CCr creatinine clearance; n.s. no significance