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Table 2 Change of renal function

From: Improvement of microcirculatory impairment in patients with predialysis chronic kidney disease after AST-120 administration

Month

-3

0

3

6

12

BUN (mg/dL)

31.3 ± 11.3

31.1 ± 12.1

31.2 ± 11.8

34.2 ± 15.4*

35.8 ± 19.8*

sCr (mg/dL)

2.02 ± 0.85

2.03 ± 0.85

2.07 ± 0.90

2.21 ± 1.00*

2.25 ± 1.23*

1/sCr (dL/mg)

0.571 ± 0.205

0.578 ± 0.226

0.578 ± 0.243

0.550 ± 0.251*

0.556 ± 0.263

eGFR (mL/min/1.73m2)

28.8 ± 11.6

29.3 ± 12.8

29.1 ± 13.4

27.6 ± 13.7*

28.0 ± 14.4

  1. BUN blood urea nitrogen, sCr serum creatinine, eGFR estimated glomerular filtration ratio
  2. *p < 0.05 vs. 0 month