Table 1 Baseline characteristics of donors, recipients, and organs
Characteristic | Vitamin C arm (n = 9) | Placebo arm (n = 10) | P |
|---|---|---|---|
Recipients | |||
Age (years) | 33.33 ± 14.59 | 45.20 ± 11.03 | 0.06 |
Sex (female), n (%) | 3 (33.3) | 5 (50) | 0.65 |
BMIa (kg/m2) | 22.10 (15.5-29.4) | 21.65 (19.1-25.4) | 0.96 |
Cause of ESKDb, n (%) | 0.27 | ||
Hypertension | 2 (22.2) | 1 (10.0) | |
Diabetes mellitus | 2 (22.2) | 0 | |
Glomerulonephritis | 2 (22.2) | 2 (20.0) | |
PKDc | 0 | 2 (20.0) | |
Drug-induced | 0 | 2 (20.0) | |
Other causes | 3 (33.3) | 3 (30.0) | |
Type of dialysis, n (%) | 0.08 | ||
Hemodialysis | 6 (66.7) | 10 (100.0) | |
Peritoneal dialysis | 3 (33.3) | 0 | |
Duration of dialysis (months) | 24 (6-42) | 20 (5-240) | 0.83 |
History of blood transfusion, n (%) | 7 (77.8) | 8 (80.0) | 0.58 |
PRAd (%) | 0 | 0 | > 0.99 |
24-h residual diuresis (ml) | 200 (0-1500) | 350 (0-1500) | > 0.99 |
Donors | |||
Age (years) | 27.89 ± 10.79 | 39.00 ± 11.74 | 0.047 |
Sex (female), n (%) | 4 (44.4) | 2 (20) | 0.35 |
BMI (kg/m2) | 24.14 ± 2.24 | 27.30 ± 4.78 | 0.092 |
CPRe, n (%) | 3 (33.3) | 2 (20.0) | 0.62 |
Hypertension, n (%) | 0 | 1 (10.0) | > 0.99 |
Diabetes mellitus, n (%) | 0 | 0 | > 0.99 |
SCrf (mg/dL) | 1.23 ± 0.27 | 1.14 ± 0.29 | 0.51 |
Last eGFRg before donation (ml/min/1.73 m2) | 69.70 (48.40-90.60) | 78.30 (45.59-198.0) | 0.36 |
ECDh, n (%) | 0 | 0 | > 0.99 |
Length of ICU stay (days) | 3 (1-5) | 4 (1-15) | 0.28 |
Transplantation | |||
Duration of surgery (min) | 210 (195-300) | 210 (180-360) | 0.27 |
Cold ischemic time (min) | 195.56 ± 77.35 | 221.30 ± 70.45 | 0.45 |
ABO incompatibility, n (%) | 0 | 0 | > 0.99 |