Table 1 Possible reasons for genetic testing of ADTKD

I

Adults with CKD suspected to have ADTKD who wish to confirm the diagnosis

II

Members of affected families with normal kidney function who wish to donate a kidney

III

Healthy adult individuals at risk who are interested in establishing a genetic diagnosis

IV

Adults interested in undergoing preimplantation genetic diagnosis to avoid their childʼs inheritance of a disease-causing mutant allele

V

Children suspected of having a REN mutation