Skip to main content

Table 1 Possible reasons for genetic testing of ADTKD

From: Prevalence of inherited changes of uric acid levels in kidney dysfunction including stage 5 D and T: a systematic review

I Adults with CKD suspected to have ADTKD who wish to confirm the diagnosis
II Members of affected families with normal kidney function who wish to donate a kidney
III Healthy adult individuals at risk who are interested in establishing a genetic diagnosis
IV Adults interested in undergoing preimplantation genetic diagnosis to avoid their childʼs inheritance of a disease-causing mutant allele
V Children suspected of having a REN mutation
  1. ADTKD autosomal-dominant tubulointerstitial kidney disease, CKD chronic kidney disease
  2. Adapted from Eckardt et al, KI 2015