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Table 1 Patients divided according to extracellular water adjusted for height ratio (aECW) prior to their mid-week dialysis session

From: Patient-reported symptoms during dialysis: the effect of pre-dialysis extracellular water and change in extracellular water post-dialysis

 

Lower aECW L/m

Middle aECW L/m

Higher aECW L/m

Number

169

172

165

Male (%)

60 (19.1)

112 (35.7)

142 (45.2) ***

Age years

66.3 ± 16.2

64.6 ± 16.9

62.7 ± 13.6

Diabetic (%)

65 (27.8)

71 (31.4)

90 (39.8)**

Co-morbidity

1 (1–2)

1.5 (1–2)

2 (1–2)

Frailty

4 (3–6)

4 (3–5)

4 (3–5)

Distress thermometer

3 (0–5)

4 (0–5)

4 (1–6)

Dialysis months

28.6 (10.8–59.8)

26.5 (7.5–61.7)

24.2 (10.8–60.9)

BMI kg/m2

22.9 ± 4.9

25.1 ± 5.4

28.4 ± 6.3***

Fat Index kg/m2

8.2 ± 4.2

8.0 ± 5.4

8.0 ± 5.7

FFMI kg/m2

14.8 ± 1.6

17.3 ± 1.4

20.3 ± 2.1***

SBP pre mmHg

141.3 ± 26.1

143.5 ± 23.8

144.8.0 ± 23.4*

SBP post mmHg

131.7 ± 27.0

134.5 ± 25.7

138.2 ± 24.9

Fall in SBP mmHg

8 (− 3 to 20)

8.5 (− 9 to 27)

6 (− 5 to 24)

Dialysate Na mmol/L

138 (136–138)

137 (136–138)

136 (136–138)***

Na serum-dialysate

2 (− 1 to + 4)

2 (0 to + 4)

3 (+ 1 to + 5)**

Dial temperature °C

35.5 (35.0–35.5)

35.5 (35.0–36.0)

35.5 (35.0–35.5)

UFR mL/kg/h

6.39(3.93–9.25)

5.52(3.55–8.65)

5.81(4.14–7.53)

% weight change

2.29(1.35–2.97)

2.04(1.17–3.13)

2.20(1.59–2.92)

Haemoglobin g/L

115.2 ± 12.2

108.3 ± 14.2

105.9 ± 15.2***

Urea mmol/L

18.6 ± 6.6

19.0 ± 6.9

20.7 ± 5.8**

Glucose mmol/L

6.3 (5.5–8.2)

6.2 (5.4–7.8)

6.8 (5.6–8.9)

Albumin g/L

38.9 ± 4.7

39.2 ± 5.2

39.1 ± 4.5

CRP mg/L

6 (2–14)

6 (2–14)

6 (2–12)

NTproBNP ng/L

4215(1538–10878)

4098(1752–13477)

5496(1786–15436)

Serum β2M mg/L

28.1 (23.1–32.5)

26.8 (22.7–32)

25.6 (21.6–30.8)

% prescribed BP meds

61.3

61.5

62.9

1 BP med %

36.3

37.9

36.5

2 BP meds %

17.3

14.2

17.6

3 or more BP meds %

8.3

8.9

9.0

ACEI/ARB %

10.1/9.5

5.3/9.5

11.4/5.4

CCB %

22.6

20.7

24.6

Beta blocker %

40.5

43.2

46.7

Alpha blocker %

13.1

14.8

12.0

  1. Data as integer, percentage, mean ± standard deviation, median, and interquartile range
  2. BMI body mass index, FFMI fat free mass index, SBP systolic blood pressure, Na sodium, Dial temperature dialysate temperature, UFR ultrafiltration rate, CRP C reactive protein, NTproBNP N terminal probrain natriuretic peptide, β2 M β 2 microglobulin, BP meds prescription of anti-hypertensive medications, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker
  3. *p < 0.05, **< 0.1, ***< 0.001 vs lowest tertile