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Table 1 Patients divided according to extracellular water adjusted for height ratio (aECW) prior to their mid-week dialysis session

From: Patient-reported symptoms during dialysis: the effect of pre-dialysis extracellular water and change in extracellular water post-dialysis

  Lower aECW L/m Middle aECW L/m Higher aECW L/m
Number 169 172 165
Male (%) 60 (19.1) 112 (35.7) 142 (45.2) ***
Age years 66.3 ± 16.2 64.6 ± 16.9 62.7 ± 13.6
Diabetic (%) 65 (27.8) 71 (31.4) 90 (39.8)**
Co-morbidity 1 (1–2) 1.5 (1–2) 2 (1–2)
Frailty 4 (3–6) 4 (3–5) 4 (3–5)
Distress thermometer 3 (0–5) 4 (0–5) 4 (1–6)
Dialysis months 28.6 (10.8–59.8) 26.5 (7.5–61.7) 24.2 (10.8–60.9)
BMI kg/m2 22.9 ± 4.9 25.1 ± 5.4 28.4 ± 6.3***
Fat Index kg/m2 8.2 ± 4.2 8.0 ± 5.4 8.0 ± 5.7
FFMI kg/m2 14.8 ± 1.6 17.3 ± 1.4 20.3 ± 2.1***
SBP pre mmHg 141.3 ± 26.1 143.5 ± 23.8 144.8.0 ± 23.4*
SBP post mmHg 131.7 ± 27.0 134.5 ± 25.7 138.2 ± 24.9
Fall in SBP mmHg 8 (− 3 to 20) 8.5 (− 9 to 27) 6 (− 5 to 24)
Dialysate Na mmol/L 138 (136–138) 137 (136–138) 136 (136–138)***
Na serum-dialysate 2 (− 1 to + 4) 2 (0 to + 4) 3 (+ 1 to + 5)**
Dial temperature °C 35.5 (35.0–35.5) 35.5 (35.0–36.0) 35.5 (35.0–35.5)
UFR mL/kg/h 6.39(3.93–9.25) 5.52(3.55–8.65) 5.81(4.14–7.53)
% weight change 2.29(1.35–2.97) 2.04(1.17–3.13) 2.20(1.59–2.92)
Haemoglobin g/L 115.2 ± 12.2 108.3 ± 14.2 105.9 ± 15.2***
Urea mmol/L 18.6 ± 6.6 19.0 ± 6.9 20.7 ± 5.8**
Glucose mmol/L 6.3 (5.5–8.2) 6.2 (5.4–7.8) 6.8 (5.6–8.9)
Albumin g/L 38.9 ± 4.7 39.2 ± 5.2 39.1 ± 4.5
CRP mg/L 6 (2–14) 6 (2–14) 6 (2–12)
NTproBNP ng/L 4215(1538–10878) 4098(1752–13477) 5496(1786–15436)
Serum β2M mg/L 28.1 (23.1–32.5) 26.8 (22.7–32) 25.6 (21.6–30.8)
% prescribed BP meds 61.3 61.5 62.9
1 BP med % 36.3 37.9 36.5
2 BP meds % 17.3 14.2 17.6
3 or more BP meds % 8.3 8.9 9.0
ACEI/ARB % 10.1/9.5 5.3/9.5 11.4/5.4
CCB % 22.6 20.7 24.6
Beta blocker % 40.5 43.2 46.7
Alpha blocker % 13.1 14.8 12.0
  1. Data as integer, percentage, mean ± standard deviation, median, and interquartile range
  2. BMI body mass index, FFMI fat free mass index, SBP systolic blood pressure, Na sodium, Dial temperature dialysate temperature, UFR ultrafiltration rate, CRP C reactive protein, NTproBNP N terminal probrain natriuretic peptide, β2 M β 2 microglobulin, BP meds prescription of anti-hypertensive medications, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker
  3. *p < 0.05, **< 0.1, ***< 0.001 vs lowest tertile