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Table 3 Patients divided according to the change in extracellular water adjusted for height ratio (ΔaECW) from pre to post their mid-week dialysis session

From: Patient-reported symptoms during dialysis: the effect of pre-dialysis extracellular water and change in extracellular water post-dialysis

  Lower ΔaECW L/m Middle ΔaECW L/m HigherΔaECW L/m
Number 170 168 166
Male (%) 103 (32.8) 107 (34.1) 104 (33.1)
Age years 66.5 ± 14.6 73.3 ± 19.0 70.4 ± 16.3*
Diabetic (%) 79 (35.1) 70 (31.1) 76 (33.8)
Co-morbidity 2 (1–2) 1 (1–2) 1 (1–2)
Frailty 4 (1–5) 4 (0–5) 3 (0–5)**
Distress thermometer 4 (0–5) 3 (0–5) 4 (1–5)
Dialysis months 24.0 (4.9–63.5) 23.9 (10.8–60.0) 30.9 (10.1–61.1)
Weight kg 69.1 ± 17.7 71.8 ± 8.6 68.6 ± 15.7
% body fat 28.7(17.4–35.5) 30.8(20.6–37.8) 32.5(23.0–39.0)
FFMI kg/m2 17.4 ± 3.0 17.8 ± 2.7 17.0 ± 2.7
SBP pre mmHg 139.9 ± 23.5 144.4 ± 24.2 148.6 ± 25.5**
SBP post mmHg 135.4 ± 24.7 135.1 ± 25.7 133.8 ± 21.4
Fall in SBP mmHg 3 (− 7 to 15) 8 (− 5 to 26) 12 (− 5 to 34)***
Dialysate Na mmol/L 137.3 (136-138) 137 (136-138) 136 (136–138)
Na serum-dialysate 1 (− 1 to + 4) 2.5 (1 to + 5)** 3 (0 to + 4.5)*
Dial temperature °C 35.5 (35.0–35.5) 35.5 (35.0–36.0) 35.5 (35.0–35.5)
UFR mL/kg/h 4.4 (2.2–7.0) 5.8 (4.1−8.1)*** 7.6 (5.5−9.8)***
% weight change 1.5 (0.7−2.3) 2.1 (1.6−2.9)*** 2.7 (2.1−3.6)***
Haemoglobin g/L 106.8 ± 14.0 108.4 ± 14.5 110.5 ± 13.5*
Urea mmol/L 19.7 ± 6.1 19.7 ± 6.4 18.9 ± 7.0
Glucose mmol/L 6.1 (5.6−8.4) 6.1 (5.2−7.7) 6.8 (5.4−8.4)
Albumin g/L 37.9 ± 5.7 39.4 ± 4.3 40.3 ± 6.4**
CRP mg/L 6 (2−18) 6.5 (1−14) 5 (1−10)
NTproBNP ng/L 4820(1561−12842) 4993(1721−13542) 4053(1644−12373)
Serum β2M mg/L 26.3 (21.2−31.6) 23.3 (21.9−32.1) 28.2 (23.4−32.2)
% prescribed BP meds 61.2 61.3 63.3
1 BP med % 35.9 36.7 36.7
2 BP meds % 17.6 13.1 17.5
3 or more BP meds % 8.2 8.9 9.0
ACEI/ARB % 10/9.4 5.4/8.9 10.8/6.0
CCB % 22.4 20.2 24.7
Beta blocker % 41.8 42.3 46.4
Alpha blocker % 12.4 15.5 12.0
  1. Data as integer, percentage, mean ± standard deviation, median, and interquartile range
  2. FFMI fat-free mass index, SBP systolic blood pressure, Na sodium, dial temperature dialysate temperature, UFR ultrafiltration rate, CRP C reactive protein, NTproBNP N terminal probrain natriuretic peptide, β2 M β 2 microglobulin, BP meds prescription of anti-hypertensive medications, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker
  3. *p < 0.05, **< 0.1, ***< 0.001 vs lowest tertile