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Table 2 Associations between the high erythropoietin resistance index and risks of the primary endpoint and of all-cause death

From: Hyporesponsiveness to long-acting erythropoiesis-stimulating agent is related to the risk of cardiovascular disease and death in Japanese patients on chronic hemodialysis: observational cohort study

 

Primary endpoint

All-cause death

HR (95% CI)

P

HR (95% CI)

P

High ERI (≥ 11.31, Q4) vs. (< 11.31, Q1, Q2, and Q3)

Unadjusted

2.16 (1.05–4.42)

0.035

2.54 (1.16–5.52)

0.019

Age- and sex-adjusted

2.77 (1.33–5.78)

0.006

3.10 (1.41–6.86)

0.005

Propensity score adjusted

2.76 (1.19–6.40)

0.018

2.57 (1.05–6.27)

0.038

  1. ERI erythropoietin resistance index, HR hazard ratio, CI confidential interval
  2. Propensity score analysis was performed using a multivariate logistic regression model, including confounding variables (age, sex, dialysis facility, diabetes, history of cardiovascular disease, dialysis duration, calcium, phosphorus, albumin, hemoglobin, C-reactive protein, intact parathyroid hormone, transferrin saturation, ferritin, use of angiotensin receptor blocker or angiotensin-converting enzyme inhibitor, and Kt/V)