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Table 1 Characteristics of all groups 4 weeks after treatment

From: Triple combination therapy with telmisartan, amlodipine, and hydrochlorothiazide ameliorates albuminuria in a normotensive rat remnant kidney model

  Sham NTx + CMC NTx + T + A NTx + T +A + H
Number 10 9 8 7
HR (/min) 381 ± 16 385 ± 17 399 ± 18 383 ± 19
Systolic BP (mmHg) 117 ± 4 115 ± 4 106 ± 5 108 ± 5
Body weight (g) 460 ± 11 430 ± 12 486 ± 13# 442 ± 13
BUN (mg/dL) 16.2 ± 1.5 29.4 ± 1.6*** 27.8 ± 0.7*** 27.0 ± 1.8***
Na (mmol/L) 138 ± 2 142 ± 1 137 ± 2 134 ± 2#
K (mmol/L) 5.84 ± 0.16 5.56 ± 0.17 5.05 ± 0.18**,# 5.64 ± 0.19
Calcium (mg/dL) 9.88 ± 0.15 9.92 ± 0.16 9.82 ± 0.17 9.43 ± 0.18
Phosphate (mg/dL) 6.84 ± 0.24 7.16 ± 0.25 6.60 ± 0.27 6.97 ± 0.29
Urinary Na (nmol/day) 754 ± 57 680 ± 60 427 ± 64** 681 ± 68
  1. Data are shown as mean ± SEM
  2. Abbreviations: NTx nephrectomized, HR heart rate, CMC carboxymethylcellulose, T telmisartan, A amlodipine, H hydrochlorothiazide, BUN blood urea nitrogen, Na sodium, K potassium
  3. **p < 0.01, ***p < 0.001 vs sham, #p < 0.05 vs NTx + CMC