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Table 5 Total and ionized concentrations of magnesium and calcium according to treatment conditions in group CiDi

From: Effects of on-line hemodiafiltration regimens and dialysate composition on serum concentrations of magnesium and calcium ions

Substitution volume [L/session] Pre-dilution Post-dilution HD (n = 6) P (5 groups)
60 (n = 6) 84 (n = 6) 8 (n = 6) 16 (n = 6)
Pre-dialysis values
 Total magnesium (mg/dL) 2.32 ± 0.37 2.32 ± 0.35 2.27 ± 0.33 2.25 ± 0.32 2.32 ± 0.39 0.995
 Ionized magnesium (mmol/L) 0.53 ± 0.05 0.52 ± 0.06 0.52 ± 0.04 0.53 ± 0.05 0.52 ± 0.06 0.994
 Total calcium (mg/dL) 9.33 ± 0.76 9.27 ± 0.83 9.23 ± 0.54 9.35 ± 0.71 9.12 ± 0.59 0.979
 Ionized calcium (mmol/L) 1.13 ± 0.05 1.15 ± 0.06 1.11 ± 0.07 1.17 ± 0.06 1.14 ± 0.05 0.588
 pH 7.40 ± 0.02 7.39 ± 0.02 7.39 ± 0.03 7.40 ± 0.02 7.40 ± 0.02 7.848
Post-dialysis values
 Total magnesium (mg/dL) 1.92 ± 0.10 1.97 ± 0.12 1.85 ± 0.14 1.92 ± 0.12 1.92 ± 0.19 0.488
 Ionized magnesium (mmol/L) 0.39 ± 0.05 0.40 ± 0.04 0.38 ± 0.05 0.39 ± 0.04 0.40 ± 0.04 0.956
 Total calcium (mg/dL) 9.60 ± 0.20 9.62 ± 0.36 9.65 ± 0.19 9.67 ± 0.31 9.45 ± 0.19 0.437
 Ionized calcium (mmol/L) 1.14 ± 0.02 1.14 ± 0.01 1.13 ± 0.03 1.14 ± 0.03 1.13 ± 0.03 0.868
 pH 7.46 ± 0.01 7.46 ± 0.01 7.45 ± 0.01 7.47 ± 0.02 7.47 ± 0.02 0.557
Pre-dialysis to post-dialysis
 Total magnesium (%) 83.8 ± 8.4 86.0 ± 9.4 82.4 ± 6.9 86.1 ± 8.1 83.8 ± 9.1 0.928
 Ionized magnesium (%) 74.9 ± 7.7 75.6 ± 9.0 73.8 ± 10.3 73.3 ± 9.8 78.3 ± 10.2 0.904
 Total calcium (%) 103.3 ± 6.1 104.2 ± 5.7 104.7 ± 5.0 103.7 ± 4.6 103.9 ± 5.1 0.999
 Ionized calcium (%) 100.8 ± 4.6 99.4 ± 4.1 101.9 ± 4.4 98.1 ± 5.7 99.3 ± 5.6 0.717
 pH 100.9 ± 0.2 100.9 ± 0.2 100.9 ± 0.3 100.9 ± 0.2 101.0 ± 0.5 0.988
Removal amount
 Magnesium (mg) 104 ± 80 113 ± 87 37 ± 68 120 ± 50 141 ± 63 0.192
 Calcium (mg) 294 ± 210 222 ± 107 267 ± 134 294 ± 199 217 ± 115 0.941
Albumin leakage (g/session) 3.1 ± 0.3 3.3 ± 0.3 4.9 ± 0.7 5.1 ± 0.9 3.2 ± 0.5 0.003