Table 2 Comparison of dialysis patients in the lowest and highest antibody quartiles
From: Humoral response after BNT162b2 vaccine in Japanese hemodialysis patients
Lowest quartiles (LQ; n = 46) Anti-spike antibody IgG < 1,011 AU/mL | Highest quartiles (HQ; n = 46) Anti-spike antibody IgG > 7,688 AU/mL | P | |
|---|---|---|---|
Age | 72.0 ± 10.2 | 65.4 ± 13.3 | 0.022 |
Male/Female | 28/18 | 31/15 | 0.644 |
Dialysis vintage, months | 121 ± 128 | 133 ± 98 | 0.988 |
DM/NDM | 13/33 | 18/28 | 0.378 |
Serum albumin (g/dL) | 3.61 ± 0.25 | 3.72 ± 0.24 | 0.055 |
Lymphocytes (/mm3) | 940 ± 340 | 1219 ± 436 | 0.002 |
BNP (ng/mL) | 328 ± 310 | 270 ± 317 | 0.188 |
Kt/V | 1.42 ± 0.26 | 1.37 ± 0.31 | 0.637 |
PCR (g/kg) | 45.4 ± 11.7 | 53.3 ± 18.8 | 0.097 |
nPCR (g/kg/day) | 0.84 ± 0.19 | 0.94 ± 0.25 | 0.036 |
GNRI | 91.7 ± 5.0 | 94.7 ± 5.1 | 0.004 |
Cr index (mg/kg/day) | 86.2 ± 26.9 | 99.9 ± 28.0 | 0.024 |
BMI (kg/m2) | 21.2 ± 3.8 | 22.9 ± 4.6 | 0.048 |
Intravenous iron dose (mg/6 months) | 208 ± 194 | 205 ± 246 | 0.626 |
Current smoking (Yes/No) | 11/35 | 3/40 | 0.041 |
Steroid (Yes/No) | 9/37 | 1/45 | 0.015 |
Immunosuppressant (Yes/No) | 1/45 | 0/46 | 1.000 |
Hematological disorder (Yes/No) | 9/37 | 0/46 | 0.025 |
HBV vaccine responsiveness (Yes/No) | 10/6 | 10/6 | 1.000 |