Present case | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | ||
---|---|---|---|---|---|---|---|
Age | 60’s | 40’s | 66 | 77 | 5 | 44 | |
Sex | Male | Male | Male | Male | Girl | Female | |
Underlying condition | ESKD on peritoneal dialysis | None specified | None specified | COPD, CAD | Acute encephalopathy, adrenal insufficiency | Breast cancer | |
Site of infection | Skin and peritoneum | Parotid gland | Prosthetic joint | Pleura | Soft tissue | Soft tissue and CVP | |
MIC (μg/mL) | Breakpoint of resistance (μg/mL) | ||||||
IPM | < 0.5 | 1 | 4 | < 0.5 | 0.5 | < 2 | ≥ 32 |
AMK | 2 | > 64 | 8 | 4 | 32 | < 8 | ≥ 64 |
CAM | 0.25 | N/A | > 32 | 16 | > 512 | > 8 | ≥ 8 |
TOB | 4 | N/A | N/A | > 16 | > 16 | N/A | ≥ 8 |
LZD | 1 | 2 | < 1 | < 4 | 8 | < 4 | ≥ 32 |
CPFX | < 0.12 | 0.5 | 32 | < 0.5 | 0.25 | 1 | ≥ 4 |
MFLX | < 0.06 | N/A | < 0.25 | < 0.25 | 0.19 | < 1 | ≥ 4 |
MINO | 0.5 | N/A | < 1 | 2 | 4 | N/A | ≥ 8 |
ST | < 0.25/4.3 | 2 | 1/19 | < 2 | > 80 | > 4 | ≥ 4/76 |
Antibiotics | IPM | LVFX | CPFX | IPM | Tosufloxacin | AMK | |
AMK | ST | ST | LVFX | LZD | CPFX | ||
CAM | AMK | ||||||
IPM | |||||||
Surgical intervention | Catheter removal | Parotid gland excision | Prosthetic joint explantation | Pleural fluid drainage | Abscess drainage | CVP removal and debridement | |
Outcome | Death due to peritonitis | Cured | Cured | Death due to aspiration pneumonia | Cured | Cured | |
Reference number | Present case | [5] | [6] | [7] | [8] | [9] |