Table 5 Genetic analysis of ATL after renal transplantation (case 1 and case 2)
Case | Specimen | Abnormal lymphocyte | Gene | Accession number | Chromosome | Exon | Nucleotide change | Amino acid change | Mutation type | Depth | VAF |
|---|---|---|---|---|---|---|---|---|---|---|---|
Case 1 | PB | 0.5% | Not found | ||||||||
Case 2 | BM | 45% | CCR4 | NM_005508 | 3 | 2 | c.C987A | p.C329X | stopgain | 381 | 0.693 |
TBL1XR1 | NM_024665 | 3 | 14 | p.S459N | c.G1376A | nonsynonymous SNV | 269 | 0.465 | |||
TP53 | NM_000546 | 17 | 5 | c.559 + 1G > A | –- | splicing | 256 | 0.438 | |||