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Table 2 Comparison of the high (> Q3) and low (< Q1) responders in the HD group after 2 and 3 doses of m-RAN vaccine

From: Robust antibody response after the third mRNA coronavirus vaccination in Japanese hemodialysis patients

 

After 2nd doses

After 3rd doses

 < Q1 (n = 46)

 > Q3 (n = 46)

P

 < Q1 (n = 41)

 > Q3 (n = 41)

P

Age

71.5 [64.3–80.0]

67.5 [59.0–73.0]

< 0.05

72.0 [65.0–79.0]

72.0 [63.0–80.0]

N.S

Hemodialysis vintage (months)

77.5 [33.0–138.0]

83.5 [28.0–176.3]

N.S

75 [38–117]

60 [32–134]

N.S

DM/NDM

13/33

18/28

N.S

13/33

13/33

N.S

Serum albumin (g/dL)

3.6 [3.5–3.8]

3.7 [3.6–3.8]

N.S

3.7 [3.5–3.9]

3.6 [3.5–3.8]

N.S

nPCR (g/kg/day)

0.83 [0.74–0.94]

0.92 [0.79–1.09]

< 0.05

0.87 [0.77–1.02]

0.84 [0.75–1.00]

N.S

Lymphocytes (mm3)

896 [729–1,067]

1,144 [849–1,443]

< 0.01

993 [752–1,170]

1,108 [752–1,410]

N.S

Cr index (mg/kg/day)

90.0 [66.5–105.5]

104.5 [81.7–116.8]

< 0.05

91.8 [78.7–101.2]

94.3 [69.2–107.8]

N.S

Current smoking (yes/no)

11/35

3/40

0.0405

10/31

3/38

N.S

Steroid (yes/no)

9/37

1/45

< 0.05

6/35

1/40

N.S

Immunosuppressant (yes/no)

1/45

0/45

N.S

4/37

2/39

N.S

Hematologic disorder (yes/no)

9/37

0/46

< 0.05

4/37

0/39

N.S

  1. Results are shown as the median [interquartile range] for continuous variables or as numbers of patients (percentages) for categorical variables. The Mann–Whitney test and Fisher exact test were used to compare continuous and categorical variables
  2. nPCR normalized protein catabolic rate, Cr creatinine