Table 4 Baseline characteristics, gasometric variables and serum renal biomarkers according to the ABE cutoff point
From: Alactic base excess predicts the use of renal replacement therapy in patients with septic shock
Variable | ABE ≤ − 5.7 n = 65 | ABE > − 5.7 n = 99 | p value |
|---|---|---|---|
Renal replacement therapy, Yes n (%) | 38 (58.5) | 30 (30.3) | < 0.0005* |
Age, years old (IQR) | 62 (17.5) | 57 (26) | 0.351 |
Gender | 0.019* | ||
Female, n (%) | 41 (63.1) | 44 (44.4) | |
Male, n (%) | 24 (36.9) | 55 (55.6) | |
Comorbidities n (%) | |||
DM, Yes | 37 (56.9) | 36 (36.4) | 0.010* |
SAH, Yes | 34 (52.3) | 48 (48.5) | 0.632 |
Heart disease, Yes | 12 (18.5) | 11 (11.1) | 0.185 |
Etiology, n (%) | 0.001* | ||
Lung, Yes | 15 (23.1) | 53 (53.5) | |
Abdominal, Yes | 30 (46.2) | 34 (34.3) | |
Urinary, Yes | 14 (21.5) | 10 (10.1) | |
Soft tissues, Yes | 2 (3.1) | 1 (1) | |
Other | 4 (6.2) | 1 (1) | |
Norepinefrine mcg/kg/min (IQR) | 0.32 (0.32) | 0.28 (0.29) | 0.077 |
Inotropic, Yes n (%) | 6 (9.2) | 15 (15.2) | 0.267 |
MV, days (IQR) | 4 (5) | 4 (5) | 0.170 |
ICU STAY, days (IQR) | 5 (5) | 6 (6) | 0.062 |
SAPS II, points (IQR) | 70 (13.5) | 71 (18) | 0.926 |
Mortality, Yes n (%) | 34 (52.3) | 49 (49.5) | 0.725 |
pH | 7.25 (0.11) | 7.34 (0.11) | < 0.001* |
PaO2/FiO2, mmHg (IQR) | 105 (65) | 90 (58) | 0.003* |
PaCO2, mmHg (IQR) | 33 (11) | 38 (11) | < 0.001* |
SBE, mmol/L (SD) | − 13.6 (5.45) | − 4.5 (4.9) | < 0.001* |
HCO3−, mmol/L (SD) | 13.6 (4.35) | 20.4 (5.2) | < 0.001* |
Lactate, mmol/L (IQR) | 3.8 (2.4) | 2.8 (2.2) | 0.004* |
AG, mEq/L (IQR) | 17 (6.5) | 13 (5.7) | < 0.001* |
Na–Cl, mEq/L (IQR) | 31 (4.5) | 33 (6) | < 0.001* |
SCr, mg/dL (IQR) | 2.9 (2.75) | 1.8 (1.8) | < 0.001* |
Urea, mg/dL (IQR) | 100 (63.75) | 64 (70.3) | < 0.001* |