Skip to main content

Table 2 Changes in biochemical parameters after 6 and 12 months from HCV eradication and SVR

From: The impact of HCV eradication using interferon-free direct acting antivirals on bone-mineral, anemia parameters and peripheral insulin resistance in hepatitis c-infected Egyptian hemodialysis cohort

Biochemical parameters

Baseline (mean ± SD)

After 6 months (mean ± SD)

After 12 months (mean ± SD)

p value

HB conc. (g/dL)

9.8 ± 1.8

11.3 ± 0.6

11.7 ± 0.6

< 0.001

Iron (mcg/dl)

52.85 ± 24.2

65.85 ± 24.2

90.85 ± 24.2

< 0.001

TSAT (%)

18 ± 9.6

22.40 ± 9.49

28.23 ± 9.12

 < 0.001

Ferritin (ng/ml)

333.75 ± 377.41

163.7 ± 21.8

128.8 ± 22.7

< 0.001

Corrected calcium (mg/dl)

8.2 ± 0.8

8.5 ± 0.3

9 ± 0.4

< 0.001

Phosphorous (mg/dl)

5.1 ± 0.8

5.2 ± 0.4

4.8 ± 0.4

< 0.001

Serum iPTH (pg/mL)

358.3 ± 177

400.4 ± 83.6

365.4 ± 84.5

< 0.001

Fasting Insulin level (mlU/L)

53.1 ± 16.1

43.1 ± 15.5

< 0.001

HOMA-IR

15.08 ± 4.95

12.15 ± 4.66

< 0.001

FGF23 Level (u/ml)

256.4 ± 24.2

234.5 ± 24

< 0.001

  1. HB: Hemoglobin, TSAT: Transferrin Saturation, HOMA-IR: HOMA insulin resistance, FGF23: Fibroblast growth factor 23