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Table 1 Clinical and laboratory findings in the studied patients (n = 100)

From: Diaphragmatic dysfunction in hemodialysis patients: risk factors and effect of incentive spirometry training

 

All patients

N = 100

Diaphragmatic dysfunction + ve

n = 43

Diaphragmatic dysfunction −ve

n = 57

p value

Age (years) mean ± SD

60.7 ± 8.7

60.5 ± 9.1

60.9 ± 8.5

0.83

Male/female n (%)

55 (55.0)/45 (45.0)

29 (67.4)/14 (32.6)

26 (45.6)/31(54.4)

0.03

BMI (Kg/m2)

25.2 ± 3.8

23.8 ± 3.8

26.3 ± 3.5

 < 0.001

Comorbidities n (%)

HTN

54 (54.0)

22 (51.2)

32 (56.1)

0.62

DM

41 (41.0)

18 (41.9)

23 (40.4)

0.88

RA

15 (15.0)

6 (14.0)

9 (15.8)

0.8

SLE

8 (8.0)

5 (11.6)

3 (5.3)

0.25

HD duration (months) mean ± SD

72.4 ± 40.0

82.2 ± 42.1

64.8 ± 36.9

0.031

Malnutrition n (%)

No/Mild

34 (34.0)

8 (18.6)

31 (54.4)

0.005

Moderate/severe

66 (66.0)

35 (81.4)

26 (45.6)

Laboratory findings mean ± SD/median (IQR)

Hb (gm/dL)

10.0 ± 1.5

9.6 ± 1.5

10.3 ± 1.4

0.011

WBCs (× 103/mL)

6.1 ± 2.0

6.4 ± 2.0

5.8 ± 1.9

0.09

Platelets (× 103/mL)

196.7 ± 58.5

190.4 ± 65.0

201.5 ± 53.2

0.35

Creatinine (mg/dL)

7.8 ± 2.5

7.5 ± 2.4

8.0 ± 2.5

0.31

Urea (mg/dL)

112.7 ± 32.1

115.2 ± 33.0

110.8 ± 31.6

0.5

FBS (mg/dL)

125.3 ± 46.7

127.6 ± 49.2

123.6 ± 45.1

0.67

Albumin (gm/dL)

3.8 ± 0.6

3.4 ± 0.4

4.1 ± 0.5

 < 0.001

Cholesterol (mg/dL)

171.5 ± 48.2

183.4 ± 52.9

162.5 ± 42.6

0.031

Triglycerides (mg/dL)

181.8 ± 107.4

194.7 ± 113.1

172.0 ± 102.8

0.29

Calcium (mg/dL)

8.8 ± 0.8

8.4 ± 0.8

9.0 ± 0.7

 < 0.001

Phosphorus (mg/dL)

4.5 ± 1.2

4.2 ± 1.1

4.7 ± 1.3

0.067

Sodium (mEq/L)

136.2 ± 5.7

133.0 ± 5.2

138.6 ± 4.8

 < 0.001

Potassium (mEq/L)

4.7 ± 0.6

4.4 ± 0.6

4.7 ± 1.3

 < 0.001

iPTH (pg/mL)

366.5 (187.0–909.8)

395.0 (206.0–904.0)

338.0 (175.0–930.0)

0.79

Uric acid (mg/dL)

5.9 ± 1.3

6.0 ± 1.4

5.8 ± 1.2

0.61

hsCRP (mg/L)

100.6 (75.9–116.6)

113.6 (90.9–130.4)

91.1 (50.9–105.6)

 < 0.001

  1. BMI Body mass index, DM Diabetes mellitus, FBS Fasting blood sugar, Hb Hemoglobin, HD Hemodialysis, hsCRP High-sensitivity C-reactive protein, HTN Hypertension, iPTH Intact parathyroid hormone, RA Rheumatoid arthritis, SLE Systemic lupus erythematosus, WBCs White blood cells