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Table 1 Patient characteristics at BL

From: Long-term treatment of evocalcet in hemodialysis patients with secondary hyperparathyroidism: a five-year prospective cohort study in 147 Japanese patients

Characteristic

Unit

All patients

n = 147

Patient background

 Gender (male)

n (%)

105 (71.4)

 Age

Years

67.2 (61.4–71.8)

 Dialysis history

Years

10.3 (5.6–17.1)

 DW

kg

60.8 ± 13.5

Primary cause of ESRD

 CGN

n (%)

69 (46.9)

 DM

n (%)

51 (34.7)

 PKD

n (%)

11 (7.5)

 NC

n (%)

5 (3.4)

 RPGN

n (%)

2 (1.4)

 Others · Unknown

n (%)

9 (6.1)

Dialysis condition

 3 times/week

n (%)

147 (100)

 Time (4 h)

n (%)

130 (88.4)

 Blood flow

mL/min

220 (200–250)

 Modality (hemodialysis)

n (%)

81 (55.1)

          (hemodiafiltration)

n (%)

66 (44.9)

 Dialysate Ca (2.5 mEq/L)

n (%)

98 (66.7)

              (3.0 mEq/L)

n (%)

49 (33.3)

Blood chemistries

 cCa

mg/dL

8.75 ± 0.57

 P

mg/dL

5.10 ± 1.13

 Mg

mg/dL

2.44 + 0.39

 i-PTH

pg/mL

142 (92–230)

 ALP

U/L

263 (212–344)

 Alb

g/dL

3.7 (3.4–3.9)

Prescription status

 Cinacalcet dose

mg/day

25 (12.5–37.5)

 Phosphate binder user

n (%)

128 (87.1)

 Ca carbonate user

n (%)

97 (66.0)

              Dose

g/day

2.5 (1.5–3.0)

 Oral VDRA user

n (%)

31 (21.1)

 Alfacalcidol dose

μg/day

0.5 (0.25–0.5)

 Calcitriol dose

μg/day

0.25 (0.25–0.25)

 Intravenous VDRA user

n (%)

96 (65.3)

                  Dose

μg/month

4.5 (2.5–6.5)

  1. BL baseline, DW dry weight, ESRD end-stage renal disease, CGN chronic glomerulonephritis, DM diabetes mellitus, PKD polycystic kidney disease, NC nephrocalcinosis, RPGN rapidly progressive glomerulonephritis, cCa corrected calcium, P phosphorus, Mg magnesium, i-PTH intact parathyroid hormone, ALP alkaline phosphatase, Alb albumin, Ca calcium, VDRA vitamin D receptor activator