Efficacy of polymethylmethacrylate membrane hemodiafilter Filtryzer® PMF™-21A in improving pruritus in hemodialysis patients: a prospective interventional study

Table 2 Changes over time in secondary endpoints (n = 20)

	Baseline	Week 4	Week 8	Week 12	p value
WBC, /μL	5295 [4462.5, 7017.5]	5630 [4290.0, 6732.5]	5655 [4492.5, 7405.0]	6060 [4530.0, 6647.5]	0.463*
Hb, g/dL	11.4 [10.8, 12.0]	11.5 [10.6, 11.9]	11.1 [10.5, 11.7]	11.5 [10.8, 11.9]	0.295*
Plt, 10⁴/μL	19.5 [17.8, 21.3]	18.5 [17.2, 20.6]	19.0 [16.6, 22.3]	18.8 [16.6, 22,7]	0.514*
Alb, g/dL	3.5 [3.4, 3.6]	3.5 [3.4, 3.7]	3.5 [3.3, 3.7]	3.6 [3.4, 3.7]	0.247*
hsCRP, mg/L	0.78 [0.29, 2.21]	0.46 [0.25, 1.62]	0.82 [0.25, 2.15]	0.56 [0.25, 1.78]	0.142*
IL-6, pg/mL	7.2 [5.9, 21.3]	7.7 [4.7, 9.7]	8.3 [6.1, 13,1]	9.2 [4.6, 11.4]	0.814*
DW, kg	54.9 [47.0, 60.6]	54.9 [48.0, 60.4]	54.9 [48.4, 60.4]	54.4 [48.4, 60.6]	0.974*
β₂-MG, mg/L	25.1 [19.7, 27.6]			27.2 [21.8, 28.9]	< 0.05**
Corrected Ca, mg/dL	8.5 [8.3, 9.1]	8.4 [8.1, 8.9]	8.6 [8.2, 8.9]	8.5 [8.1, 8.8]	0.300*
IP, mg/dL	5.1 [4.7, 5.5]	4.8 [4.2, 5.2]	4.7 [3.9, 5.1]	4.5 [4.1, 5.1]	0.295*
Whole PTH, pg/mL	100.2 [73.6, 136.3]			83.5 [53.7, 154.7]	0.823**

Data are presented as median [IQR]. P values were calculated using the Friedman test (*) or Wilcoxon signed rank sum test (**)
Alb albumin, β₂-MG β₂-microglobrin, corrected Ca corrected calcium, DW dry weight, Hb hemoglobin, hsCRP high-sensitivity C-reactive protein, IL-6 interleukin-6, IP inorganic phosphorus, IQR interquartile range, Plt platelets, PMF-21A Filtryzer® PMF™-A, WBC white blood cells, Whole PTH whole parathyroid horomone

ISSN: 2059-1381