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  1. Content type: Review

    Peritoneal dialysis (PD)-related infection encompasses PD-related peritonitis and catheter-related infections, and the latter is used as the collective term to describe exit site infection (ESI) and tunnel inf...

    Authors: Cheuk Chun Szeto

    Citation: Renal Replacement Therapy 2018 4:7

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  2. Content type: Research

    The management of renal anemia in the pre-dialysis period has been remarkably improved by long-acting erythropoiesis-stimulating agents (ESA). However, many incident dialysis patients cannot achieve target hem...

    Authors: Shinya Kawamoto, Yu Kaneko, Hideo Misawa, Katsuhiro Nagahori, Atsushi Kitazawa, Atsunori Yoshino and Tetsuro Takeda

    Citation: Renal Replacement Therapy 2018 4:4

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  3. Content type: Research

    Chronic kidney disease (CKD) is an important global health challenge with increasing burden worldwide. CKD and acute kidney injury (AKI) may require renal replacement therapy (RRT) at some stages of the diseas...

    Authors: E. K. Tannor, Y. A. Awuku, V. Boima and S. Antwi

    Citation: Renal Replacement Therapy 2018 4:3

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  4. Content type: Case Report

    Purple color of urine is alarming and may indicate a serious underlying pathology. Purple discoloration of the urinary catheter bag is uncommon and is caused by urinary tract infection with certain organisms.

    Authors: Ankit Kayal, Shashanka Dhanuka, Bibhas Chandra Mukhopadhyay, Tapan Kumar Mandal and Charu Lata Bansal

    Citation: Renal Replacement Therapy 2017 3:52

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  5. Content type: Research

    Nutritional therapy and exercise training (ET) are important interventions for hemodialysis patients. We investigated the status of nutritional therapy and ET provided at hemodialysis facilities across Japan.

    Authors: Satoko Sakurai, Norio Hanafusa, Hideki Kato, Shinji Iizaka, Ryoko Murayama and Masaomi Nangaku

    Citation: Renal Replacement Therapy 2017 3:60

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  6. Content type: Research

    Intradialytic hypotension (IDH) is a common clinical manifestation associated with poor prognosis in hemodialysis (HD) patients. HD patients who suffer from diabetic nephropathy (DN) are increasing and diabete...

    Authors: Kenji Tsuchida, Hirofumi Hashimoto, Kazuhiko Kawahara, Ikuro Hayashi, Yoshio Fukata, Munenori Kashiwagi, Akihiro C. Yamashita, Michio Mineshima, Tadashi Tomo, Ikuto Masakane, Yoshiaki Takemoto, Hideki Kawanishi, Kojiro Nagai and Jun Minakuchi

    Citation: Renal Replacement Therapy 2017 3:58

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  7. Content type: Research

    Carnitine is reported to improve insulin resistance and reduce oxidative stress. Hyperglycemia and increased oxidative stress are well known to promote the production of advanced glycation end products (AGEs) ...

    Authors: Yumi Kamada, Takashi Masuda, Kazuhiko Kotani, Shinya Tanaka, Takeshi Nakamura, Nobuaki Hamazaki, Yoko Itoh, Ibuki Moriguchi, Naoyuki Kobayashi, Michihito Okubo, Kazuhiro Takeuchi, Shokichi Naito and Yasuo Takeuchi

    Citation: Renal Replacement Therapy 2017 3:57

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  8. Content type: Case Report

    In the present report case, we show a peritonitis infection in a continuous ambulatory peritoneal dialysis (CAPD) patient in Colombia. We isolated Rhodococcus equi in the peritoneal fluid culture. Rhodococcus equ...

    Authors: José Lucas Daza, Yaroslad De La Cruz, Jesús Morales, Carolina Molina, Mauricio Duque, Ingrid Prieto and Victoria Ballen

    Citation: Renal Replacement Therapy 2017 3:59

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  9. Content type: Research

    Nalfurafine hydrochloride (“nalfurafine”), the world’s first selective oral κ-receptor agonist for improving pruritus, is approved in Japan for the treatment of pruritus resistant to existing treatments in hem...

    Authors: Hidetomo Nakamoto, Takanori Oh, Masahiro Shimamura, Eiji Iida and Sadanobu Moritake

    Citation: Renal Replacement Therapy 2017 3:51

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  10. Content type: Research

    The reported prevalence rate of depressive symptoms in hemodialysis patients is 40%. Although appropriate management of these symptoms is important, they remain under-recognized and under-treated in hemodialys...

    Authors: Takahiro Shimoda, Ryota Matsuzawa, Keika Hoshi, Kei Yoneki, Manae Harada, Takaaki Watanabe and Atsuhiko Matsunaga

    Citation: Renal Replacement Therapy 2017 3:56

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  11. Content type: Research

    A lot of risk factors for mortality have been proposed in hemodialysis patients. However, most of the findings were derived from the analyses using all of the hemodialysis patients. What we really want to know...

    Authors: Kojiro Nagai, Sayo Ueda, Kenji Tsuchida, Toshio Doi and Jun Minakuchi

    Citation: Renal Replacement Therapy 2017 3:55

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  12. Content type: Research

    The inferior vena cava (IVC) dimensions represent the right ventricular preload, whereas the peak early mitral inflow wave velocity (peak E-velocity) represents the left ventricular preload. On the other hand,...

    Authors: Kazuo Kimura, Katsuya Kajimoto, Shigeru Otsubo, Takashi Akiba and Kosaku Nitta

    Citation: Renal Replacement Therapy 2017 3:54

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  13. Content type: Case Report

    Patients with end-stage renal disease are in an immune-compromised state, with infection being the most common cause of mortality among those undergoing dialysis.

    Authors: Manabu Hayata, Junji Yamashita, Kentaro Tokunaga, Masashi Ejima, Katsuyuki Sagishima, Shigeki Nakagawa, Daisuke Hashimoto, Hideo Baba, Kosuke Maruyama, Yu Kohrogi, Teruhiko Mizumoto, Masashi Mukoyama and Hidenobu Kamohara

    Citation: Renal Replacement Therapy 2017 3:53

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  14. Content type: Case Report

    Methotrexate (MTX), a folic acid antimetabolite, is administered at a high dose for the treatment of diseases such as leukemia and malignant lymphoma. Often, an effort is made to reduce the adverse effects of ...

    Authors: Emi Fujikura, Maho Akiu, Kenichiro Miyauchi, Mai Yoshida, Satoshi Aoki, Tae Yamamoto, Kaori Narumi, Noriko Yanagisawa, Takashi Nakamichi, Mariko Miyazaki, Hiroshi Sato and Sadayoshi Ito

    Citation: Renal Replacement Therapy 2017 3:48

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  15. Content type: Research

    How residual kidney function (RKF) functions in the prevention of anemia in peritoneal dialysis (PD) patients is unclear. In this study, we investigated the association between RKF and hemoglobin (Hb) level.

    Authors: Kazuhiko Tsuruya, Kumiko Torisu, Hisako Yoshida, Shunsuke Yamada, Shigeru Tanaka, Akihiro Tsuchimoto, Masahiro Eriguchi, Kiichiro Fujisaki, Kosuke Masutani and Takanari Kitazono

    Citation: Renal Replacement Therapy 2017 3:47

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  16. Content type: Case Report

    Trimethoprim–sulfamethoxazole (TMP/SMX) is an essential antimicrobial agent for treating pneumocystis pneumonia (PCP). Furthermore, the risk of hypoglycemia is increased with the co-administration of sulfonylu...

    Authors: Arata Hibi, Yusuke Kuga, Chiharu Ito, Toshiyuki Miura, Satoru Kominato, Keisuke Kamiya, Keisuke Kamiya, Takahisa Kasugai and Katsushi Koyama

    Citation: Renal Replacement Therapy 2017 3:45

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  17. Content type: Research

    The treatment of Kawasaki disease is controversial when intravenous immunoglobulin therapy fails, although it typically relies on combinations of prednisolone, infliximab, cyclosporine, and plasma exchange the...

    Authors: Yusuke Kaida, Takatoshi Kambe, Shintaro Kishimoto, Yusuke Koteda, Kenji Suda, Ryo Yamamoto, Tetsurou Imai, Takuma Hazama, Yoshimi Takamiya, Ryo Shibata, Hidemi Nishida, Seiya Okuda and Kei Fukami

    Citation: Renal Replacement Therapy 2017 3:50

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  18. Content type: Research

    Secondary hyperparathyroidism (SHPT) is associated with higher cardiovascular risk and mortality in patients undergoing dialysis. Cinacalcet hydrochloride (CH), which has been clinically available in Japan sin...

    Authors: Akiko Takeshima, Hiroaki Ogata, Yoshiyuki Kadokura, Yoshihiro Yamada, Kei Asakura, Tadashi Kato, Yoshinori Saito, Kantaro Matsuzaka, Go Takahashi, Masanori Kato, Masahiro Yamamoto, Hidetoshi Ito and Eriko Kinugasa

    Citation: Renal Replacement Therapy 2017 3:49

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  19. Content type: Case Report

    The authors herein report a case of paradoxical cerebral infarction by spraying thrombus in the catheter for dialysis. The clinical manifestations of paradoxical cerebral infarction are nonspecific, and the di...

    Authors: Seiji Hashimoto, Hiroyoshi Sasaki, Hiroshi Matsuura, Takao Koike and Tomoaki Haga

    Citation: Renal Replacement Therapy 2017 3:44

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  20. Content type: Research

    We evaluated the biocompatibility and small protein permeability of a newly developed hydrophilic-coated membrane dialyzer (NV) compared with conventional polysulfone dialyzer (APS) for hemodialysis (HD) therapy.

    Authors: Hirotoshi Kodama, Akira Tsuji, Akihiro Fujinoki, Koujirou Ooshima, Kaori Ishizeki and Tatsuo Inoue

    Citation: Renal Replacement Therapy 2017 3:40

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  21. Content type: Review

    Frailty is a clinical state in which there is an increase in the individual’s vulnerability to developing increased dependency and/or mortality when exposed to a stressor. Since the mean age of dialysis patien...

    Authors: Kosaku Nitta, Norio Hanafusa and Ken Tsuchiya

    Citation: Renal Replacement Therapy 2017 3:41

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  22. Content type: Case Report

    Okinoerabu Island and Tokunoshima Island lie in the sea to the south of the Japanese mainland, about 100 km north of Okinawa and about 500 km south of Kyushu. There are no facilities that specialize in kidney ...

    Authors: Hajime Hirano, Ryoichi Maenosono, Tomohisa Matsunaga, Hirofumi Uehara, Hayahito Nomi, Takuya Tsujino, Naoki Tanda, Kenkichi Saito, Taizo Uchimoto, Naokazu Ibuki, Teruo Inamoto, Yoshihiro Tokeshi and Haruhito Azuma

    Citation: Renal Replacement Therapy 2017 3:46

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  23. Content type: Research

    Pneumonia is common in hemodialysis (HD) patients and has a poor prognosis, but there is little information on an accurate method for evaluating the severity of pneumonia, which is closely associated with prog...

    Authors: Makoto Harada, Takeshi Masubuchi, Kazuaki Fujii, Yukifumi Kurasawa, Tohru Ichikawa and Mamoru Kobayashi

    Citation: Renal Replacement Therapy 2017 3:39

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  24. Content type: Research

    Ferric citrate hydrate (FCH), an iron-based phosphate binder, affects mineral and iron metabolism in patients with chronic kidney disease (CKD). The long-term impact of FCH on iron overload is unknown. With th...

    Authors: Maki Hiratsuka, Katsushi Koyama, Kinya Sengo, Jun Yamamoto, Aiko Narita, Chiharu Ito, Satoshi Kominato, Arata Hibi, Keisuke Kamiya, Rumi Miyahara, Junichi Fujikawa and Toshiyuki Miura

    Citation: Renal Replacement Therapy 2017 3:37

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  25. Content type: Research

    Iron-based phosphate binders are widely used in hemodialysis, to avoid the increased mortality associated with high serum phosphate in dialysis patients. However, comparative studies on the effects of phosphat...

    Authors: Takeo Ishii, Yukiko Nakajima and Kunio Oyama

    Citation: Renal Replacement Therapy 2017 3:38

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  26. Content type: Research

    Peritoneal dialysis peritonitis remains a significant cause of morbidity for peritoneal dialysis patients and the main reason for conversion from peritoneal dialysis to hemodialysis. As the characteristics of ...

    Authors: Vui Eng Phui, Clare Hui Hong Tan, Chee Kean Chen, Kee Hoe Lai, Kwek Foong Chew, Hock Hin Chua, Laura Lui Sian Ngu and Lawrence Wei Soon Hii

    Citation: Renal Replacement Therapy 2017 3:35

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  27. Content type: Research

    Newly formed membrane (NFM) on the peritoneal membrane proper is a unique pathological hallmark of encapsulating peritoneal sclerosis (EPS), but its definition and diagnostic significance have not been well de...

    Authors: Kazuho Honda, Chieko Hamada, Kunio Kawanishi, Masaaki Nakayama, Masanobu Miyazaki and Yasuhiko Ito

    Citation: Renal Replacement Therapy 2017 3:33

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  28. Content type: Research

    The production of presepsin has been shown to be strongly related to bacterial phagocytosis. The purpose of the present study is to compare the usefulness of presepsin for diagnosing localized skin wound infec...

    Authors: Jun Shiota, Hitoshi Tagawa, Norihiko Ohura and Hitoshi Kasahara

    Citation: Renal Replacement Therapy 2017 3:31

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  29. Content type: Research

    The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening method primarily developed for elderly people; it is also reported to be useful for predicting mortality in patients on maintenance dialys...

    Authors: Akihito Tanaka, Daijo Inaguma, Hibiki Shinjo, Minako Murata and Asami Takeda

    Citation: Renal Replacement Therapy 2017 3:27

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  30. Content type: Research

    Hemodialysis with polymethylmetacrylate (PMMA) membrane dialyzers allows unique protein adsorption. New PMMA dialyzers should demonstrate equivalent protein adsorption, but improved hemocompatibility.

    Authors: Ikuto Masakane, Shiho Esashi, Asami Yoshida, Tetsuro Chida, Hiroaki Fujieda, Yoshiyuki Ueno and Hiroyuki Sugaya

    Citation: Renal Replacement Therapy 2017 3:32

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  31. Content type: Research

    Acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) is associated with high mortality in critically ill patients. However, the optimal timing to initiate CRRT in patients with AKI i...

    Authors: Jun Suzuki, Tetsu Ohnuma, Hidenori Sanayama, Kiyonori Ito, Takayuki Fujiwara, Hodaka Yamada, Alan Kawarai Lefor and Masamitsu Sanui

    Citation: Renal Replacement Therapy 2017 3:30

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  32. Content type: Review

    The number of older dialysis patients is increasing in many countries. For example, the trend is linked to the increase in the dialysis patients 70 years of age and over in Japan. Older dialysis patients often...

    Authors: Norio Hanafusa, Kosaku Nitta and Ken Tsuchiya

    Citation: Renal Replacement Therapy 2017 3:29

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  33. Content type: Research

    Although it is believed that chronic kidney disease (CKD) in patients with ischemic heart disease (IHD) negatively affects physical activity after discharge, its actual influence on the physical activity of pa...

    Authors: Ryota Matsuzawa, Takashi Masuda, Kentaro Kamiya, Nobuaki Hamazaki, Kohei Nozaki, Shinya Tanaka, Emi Maekawa and Junya Ako

    Citation: Renal Replacement Therapy 2017 3:28

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  34. Content type: Review

    Sepsis due to microbial invasion often causes multiple organ failure (MOF), including acute kidney injury (AKI), with high mortality rates in serious cases. Hence, there is an urgent need for diagnostic biomar...

    Authors: Eiichi Sato, Atsuko Kamijo-Ikemori, Tsuyoshi Oikawa, Aya Okuda, Takeshi Sugaya, Kenjiro Kimura, Tsukasa Nakamura and Yugo Shibagaki

    Citation: Renal Replacement Therapy 2017 3:26

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  35. Content type: Review

    Psychonephrology is the field of study encompassing nephrology, psychiatry, and psychosomatic medicine, which is based on the concept of consultation-liaison within the biopsychosocial model of mind–body unity...

    Authors: Yoichi Ohtake

    Citation: Renal Replacement Therapy 2017 3:25

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  36. Content type: Position statement

    Renal anemia is a complication of chronic kidney disease. Guidelines for safe and effective treatment in patients with renal anemia are needed. The Japanese Society for Dialysis Therapy (JSDT) published guidel...

    Authors: Hiroyasu Yamamoto, Shinichi Nishi, Tadashi Tomo, Ikuto Masakane, Kazuhide Saito, Masaomi Nangaku, Motoshi Hattori, Takahiro Suzuki, Satoshi Morita, Akira Ashida, Yasuhiko Ito, Takahiro Kuragano, Yasuhiro Komatsu, Ken Sakai, Yoshiharu Tsubakihara, Kazuhiko Tsuruya…

    Citation: Renal Replacement Therapy 2017 3:36

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  37. Content type: Research

    For patients undergoing hemodialysis, continuing in labor is very challenging and many patients have difficulty in current and/or previous workplaces. The objective of the present study is to clarify the deter...

    Authors: Hideyo Tsutsui, Kyoko Nomura, Aya Ishiguro, Yoshinari Tsuruta, Sawako Kato, Yoshinari Yasuda, Shunya Uchida and Yoshiharu Oshida

    Citation: Renal Replacement Therapy 2017 3:23

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  38. Content type: Research

    We recently demonstrated, using an index of recently synthesized hemoglobin, reticulocyte hemoglobin (Ret-Hb), that iron administration remarkably improves hemoglobin (Hb) synthesis during the period of high a...

    Authors: Tomoyuki Kawano, Tadashi Kuji, Tetsuya Fujikawa, Eiko Ueda, Midori Shino, Satoshi Yamaguchi, Toshimasa Ohnishi, Kouichi Tamura, Nobuhito Hirawa and Yoshiyuki Toya

    Citation: Renal Replacement Therapy 2017 3:20

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  39. Content type: Position statement

    Since 2009, the peritoneal dialysis (PD) registry has been carried out as part of Japanese Society for Dialysis Therapy (JSDT) Renal Data Registry with the cooperation of Japanese Society for Peritoneal Dialys...

    Authors: Ikuto Masakane, Takeshi Hasegawa, Satoshi Ogata, Naoki Kimata, Shigeru Nakai, Norio Hanafusa, Takayuki Hamano, Kenji Wakai, Atsushi Wada and Kosaku Nitta

    Citation: Renal Replacement Therapy 2017 3:21

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  40. Content type: Position statement

    The Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT) has developed 14 clinical practice guidelines (CPGs) and their revised editions independently or in cooperation with other organ...

    Authors: Kosaku Nitta, Ikuto Masakane, Tadashi Tomo, Kenji Tsuchida, Kiyoshi Ikeda, Tomonari Ogawa, Eiichiro Kanda, Yoshihiko Kanno, Yasuhiro Komatsu, Masatomo Taniguchi, Fumika Taki, Takeshi Hasegawa, Norio Hanafusa, Takayuki Hamano, Masafumi Fukagawa, Jun Minakuchi…

    Citation: Renal Replacement Therapy 2017 3:34

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  41. Content type: Research

    In recent years, the use of chest ultrasonography to detect lung water has received growing attention in clinical research. Estimation of the number of B-lines using lung ultrasound is now a standard method fo...

    Authors: Shinzo Kuzuhara, Shigeru Otsubo, Katsuya Kajimoto, Takashi Akiba and Kosaku Nitta

    Citation: Renal Replacement Therapy 2017 3:17

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  42. Content type: Review

    Peritonitis is an important complication of peritoneal dialysis. Several animal peritonitis models have been described, including bacterial and fungal models that are useful for studying inflammation in perito...

    Authors: Yasuhiko Ito, Hiroshi Kinashi, Takayuki Katsuno, Yasuhiro Suzuki and Masashi Mizuno

    Citation: Renal Replacement Therapy 2017 3:16

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  43. Content type: Research

    There are very few oral antidiabetic drugs recommended for patients on dialysis. Saxagliptin is known for its potent effect and long duration of action. In this study, we compared the efficacy of Saxagliptin w...

    Authors: Yukinao Sakai, Saori Sakai, Koji Mugishima, Anna Katayama, Yuichiro Sumi, Yusuke Otsuka, Tomoyuki Otsuka and Shuichi Tsuruoka

    Citation: Renal Replacement Therapy 2017 3:15

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  44. Content type: Case Report

    Insulin antibody appears in approximately 40% of insulin users using human insulin and insulin analog formulations. Insulin antibody, characterized by high affinity and low insulin antibody binding capacity (%...

    Authors: Kentaro Wada, Haruhito A. Uchida and Yuko Wada

    Citation: Renal Replacement Therapy 2017 3:14

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