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  1. More than three hundred thousand hemodialysis (HD) patients exist in Japan. The average of vintage of Japanese hemodialysis patients was longer than Western country. Longer and older hemodialysis patients tend...

    Authors: Takeshi Nakata, Hirotaka Shibata, Yuji Kamijo and Tsuneo Konta

    Citation: Renal Replacement Therapy 2021 7:14

    Content type: Research

    Published on:

  2. Responsiveness to erythropoiesis-stimulating agents (ESAs) is thought to be related to prognosis in patients on hemodialysis. A multi-center, prospective cohort study was conducted to investigate the effects o...

    Authors: Kenichi Tanaka, Momoko Fujiwara, Hirotaka Saito, Tsuyoshi Iwasaki, Akira Oda, Shuhei Watanabe, Makoto Kanno, Hiroshi Kimura, Yoshihiro Tani, Jun Asai, Hodaka Suzuki, Keiji Sato and Junichiro James Kazama

    Citation: Renal Replacement Therapy 2021 7:13

    Content type: Research

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  3. The impact of end-stage renal disease on the patient’s psychological status necessitates the value of increasing depression awareness. The current study aimed to assess the depression prevalence among Palestin...

    Authors: Samah W. Al-Jabi, Ansam Sous, Fatimah Jorf, Mahmoud Taqatqa, Mahdi Allan, Lamees Sawalha, Enas Lubadeh, Waleed M. Sweileh and Sa’ed H. Zyoud

    Citation: Renal Replacement Therapy 2021 7:12

    Content type: Research

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  4. Online hemodiafiltration (OL-HDF), whether in pre-dilution OL-HDF (pre-HDF) or post-dilution OL-HDF (post-HDF), is conducted to efficiently remove low molecular weight proteins from the blood of patients requi...

    Authors: Kenji Sakurai, Hiromi Hosoya, Yoshitaka Kurihara and Takeshi Saito

    Citation: Renal Replacement Therapy 2021 7:10

    Content type: Research

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  5. To manage the anemic status in hemodialysis (HD) patients, a well-balanced combination therapy based on the use of erythropoiesis-stimulating agents (ESAs) and iron supplementation is essential. Serum ferritin...

    Authors: Kumiko Onda, Teruo Koyama, Sanae Kobayashi, Yoji Ishii and Kazuo Ohashi

    Citation: Renal Replacement Therapy 2021 7:9

    Content type: Research

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  6. In continuous renal replacement therapy (CRRT), administration of anticoagulants is necessary for achieving a certain level of filter lifetime. Generally, anticoagulant doses are controlled to keep activated p...

    Authors: Hiroko Yuzawa, Yousuke Hirose, Tomonori Kimura, Keisuke Shinozaki, Moe Oguchi, Tomohiro Morito and Tomohito Sadahiro

    Citation: Renal Replacement Therapy 2021 7:7

    Content type: Research

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  7. Dialysis patients have to take many oral drugs, causing a high pill burden. Phosphate binders (PBs) account for a large proportion of daily pill burden; however, the relationship between patient background and...

    Authors: Nobuo Nagano, Kyoko Ito, Takashi Ono, Yuichi Ariyoshi, Soichiro Masima, Hajime Kobayashi, Tetsuo Ando, Takaaki Tsutsui and Tetsuya Ogawa

    Citation: Renal Replacement Therapy 2021 7:5

    Content type: Research

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  8. Quality of life for haemodialysis (HD) patients may be affected by symptoms during dialysis treatments, and patient groups have highlighted the need to improve post-dialysis fatigue and dialysis-related sympto...

    Authors: Suree Yoowannakul, Surachet Vongsanim, Kamonwan Tangvoraphonkchai, Ahmed Mohamed and Andrew Davenport

    Citation: Renal Replacement Therapy 2021 7:4

    Content type: Research

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  9. Renal anemia is the important complication in patients undergoing peritoneal dialysis (PD), and heart failure (HF) is the important complication in patients on dialysis. Decreasing endogenous erythropoietin (E...

    Authors: Kohsuke Terada, Yuichiro Sumi, Sae Aratani, Akio Hirama, Tetsuya Kashiwagi and Yukinao Sakai

    Citation: Renal Replacement Therapy 2021 7:3

    Content type: Research

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  10. Creating permanent vascular access (VA) is recommended before hemodialysis initiation in patients with end-stage renal disease (ESRD). Although many patients are still introduced to hemodialysis with temporary...

    Authors: Izaya Nakaya, Taijiro Goto, Yuki Nakamura, Kazuhiro Yoshikawa, Junji Oyama, Yoshihiko Tamayama, Mizuho Morooka, Sadatoshi Ito, Hirotaka Ishioka, Yuki Matsuura and Jun Soma

    Citation: Renal Replacement Therapy 2021 7:2

    Content type: Research

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  11. Clinical studies of anti-glomerular basement membrane (GBM) disease were limited because of the low incidence. We aimed to report the characteristics, treatments, and outcomes of patients with anti-GBM disease...

    Authors: Yoshinosuke Shimamura, Takuto Maeda, Koki Abe, Yayoi Ogawa and Hideki Takizawa

    Citation: Renal Replacement Therapy 2021 7:1

    Content type: Case Report

    Published on:

  12. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ryoichi Maenosono, Masayoshi Okumi, Kohei Unagami, Hironori Fukuda, Kazuhiko Yoshida, Yoichi Kakuta, Toshio Takagi, Junpei Iizuka, Tomokazu Shimizu, Haruhito Azuma, Yoji Nagashima, Kazunari Tanabe, Kosaku Nitta and Hideki Ishida

    Citation: Renal Replacement Therapy 2020 6:67

    Content type: Correction

    Published on:

    The original article was published in Renal Replacement Therapy 2020 6:52

  13. With the increasing prevalence and incidence of chronic renal failure leading to advanced kidney disease (ESRD), the use of renal transplant therapy is increasing globally. The aim of this study was to determi...

    Authors: Arghavan Malekshahi, Hamidreza Fallah MortezaNejad, Morteza Rahbar Taromsari, Reza Ghanei Gheshlagh and Kourosh Delpasand

    Citation: Renal Replacement Therapy 2020 6:66

    Content type: Research

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  14. Since 2015, the Committee of International Communication on Academic Research of the Japanese Society for Dialysis Therapy has held its Asian symposium during the society’s Annual Congress to discuss the prese...

    Authors: Toru Hyodo, Masafumi Fukagawa, Nobuhito Hirawa, Yoshitaka Isaka, Hidetomo Nakamoto, Pham Van Bui, Khin Thida Thwin and Chanseila Hy

    Citation: Renal Replacement Therapy 2020 6:65

    Content type: Review

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  15. Etelcalcetide is the first intravenously administered calcimimetic agent used to manage secondary hyperparathyroidism (SHPT) in hemodialysis (HD) patients. We evaluated the safety and efficacy of replacing cin...

    Authors: Yuka Kurokawa, Yusuke Kaida, Takuma Hazama, Yosuke Nakayama, Takaomi Otome, Ryo Shibata, Sakuya Ito, Goh Kodama, Nao Nakamura, Takatoshi Kambe, Tomofumi Moriyama, Akiko Nagata, Aki Minami, Ryotaro Ando, Yoshifumi Wada, Miki Sugiyama…

    Citation: Renal Replacement Therapy 2020 6:64

    Content type: Research

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  16. Gastroparesis is frequently overlooked and difficult to treat. The diagnosis of gastroparesis requires standard upper gastrointestinal endoscopy to exclude gastric outlet obstruction and objective evidence dem...

    Authors: Eriko Eguchi

    Citation: Renal Replacement Therapy 2020 6:62

    Content type: Case Report

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  17. There is a higher frequency of advanced chronic kidney disease (CKD) in frail patients than in the general population. This study evaluated frailty status before initiation of dialysis and clarified the progno...

    Authors: Masaki Yoshida, Yurie Takanashi, Takako Harigai, Noriyuki Sakurai, Keiko Kobatake, Hiroaki Yoshida, Satsuki Kobayashi, Takayuki Matsumoto and Kazue Ueki

    Citation: Renal Replacement Therapy 2020 6:60

    Content type: Research

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  18. Complications of acute kidney injury (AKI) are common in patients with coronavirus disease in 2019 (COVID-19). However, clinical characteristics of COVID-19-associated AKI are poorly described. We present two ...

    Authors: Takuya Fujimaru, Keiki Shimada, Takayuki Hamada, Kimio Watanabe, Yugo Ito, Masahiko Nagahama, Fumika Taki, Shutaro Isokawa, Toru Hifumi, Norio Otani and Masaaki Nakayama

    Citation: Renal Replacement Therapy 2020 6:59

    Content type: Case Report

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  19. The expected remaining lifetime of dialysis patients in Japan was only reported in 2003 and has not been reported thereafter. From 2003 to the present, several new therapeutic agents have been introduced. Thes...

    Authors: Shigeru Nakai, Atsushi Wada, Kenji Wakai, Masanori Abe and Kosaku Nitta

    Citation: Renal Replacement Therapy 2020 6:58

    Content type: Research

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  20. Peritoneal dialysis (PD) is associated with various complications, some of which may result in its discontinuation. Pleuroperitoneal communication (PPC) is commonly recognized by the presence of a diaphragmati...

    Authors: Jun Ino, Haruna Kaneko, Eri Kasama, Mio Kodama, Keitaro Sato, Hitoshi Eizumi and Kosaku Nitta

    Citation: Renal Replacement Therapy 2020 6:57

    Content type: Case Report

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  21. Catheter dysfunction, especially omental wrapping, is a serious complication of peritoneal dialysis (PD). Although catheter implantation at a lower site was reported to prevent omental wrapping, this method co...

    Authors: Kyohei Ogawa, Yukio Maruyama, Nanae Matsuo, Yudo Tanno, Ichiro Ohkido, Keita Hirano, Masato Ikeda and Takashi Yokoo

    Citation: Renal Replacement Therapy 2020 6:56

    Content type: Research

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  22. Renal transplant recipients with chronic kidney disease (CKD) often develop abnormal glucose metabolism. Although recent studies have reported the protective effects of sodium-glucose transport protein 2 (SGLT...

    Authors: Ryoichi Miyazaki, Kyoko Miyagi and Misaki Yoshida

    Citation: Renal Replacement Therapy 2020 6:55

    Content type: Case Report

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  23. Hemodialysis patients have a greater risk of cardiovascular disease, their major cause of death. Obesity is a risk factor for arteriosclerosis, cardiovascular disease, and mortality in the general population. ...

    Authors: Takeshi Iida, Satoshi Morimoto, Hidenobu Okuda, Yoshifumi Amari, Takatomi Yurugi, Fumitaka Nakajima and Atsuhiro Ichihara

    Citation: Renal Replacement Therapy 2020 6:54

    Content type: Research

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  24. Cholesterol embolization syndrome (CES) is a disease associating with the systemic cholesterol crystal embolism and end-organ dysfunction due to the atherosclerotic plaque rupture, which is dominantly triggere...

    Authors: Kota Kakeshita, Tsutomu Koike, Teruhiko Imamura, Yu Arisawa, Sayaka Murai, Ayako Shimizu, Taigo Kiyosawa, Hidenori Yamazaki and Koichiro Kinugawa

    Citation: Renal Replacement Therapy 2020 6:53

    Content type: Case Report

    Published on:

  25. BK polyomavirus (BKPyV) infection after kidney transplantation is an important cause of graft failure among kidney transplant recipient and may cause malignant tumor, although the association between BKPyV inf...

    Authors: Ryoichi Maenosono, Masayoshi Okumi, Kohei Unagami, Hironori Fukuda, Kazuhiko Yoshida, Yoichi Kakuta, Toshio Takagi, Junpei Iizuka, Tomokazu Shimizu, Haruhito Azuma, Yoji Nagashima, Kazunari Tanabe, Kosaku Nitta and Hideki Ishida

    Citation: Renal Replacement Therapy 2020 6:52

    Content type: Case Report

    Published on:

    The Correction to this article has been published in Renal Replacement Therapy 2020 6:67

  26. The annual survey questionnaires of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) were sent to 4458 dialysis facilities at the end of 2018; 4402 facilities (98.7%) responded to the facil...

    Authors: Kosaku Nitta, Masanori Abe, Ikuto Masakane, Norio Hanafusa, Masatomo Taniguchi, Takeshi Hasegawa, Shigeru Nakai, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Shunsuke Goto, Minako Wakasugi, Keiichi Yamamoto and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2020 6:51

    Content type: Review

    Published on:

  27. Metabolic acidosis is common in hemodialysis (HD) patients. The KDOQI guidelines therapeutic goal is pre-dialysis HCO3 ≥ 22 mmol/L. The aim of the study was to evaluate an individualized HCO3 hemodialysis presc...

    Authors: Rita Valério Alves, Hernâni Gonçalves, Karina Lopes, Flora Sofia and Ana Vila Lobos

    Citation: Renal Replacement Therapy 2020 6:50

    Content type: Research

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  28. Hypozincemia contributes to phosphate-induced vascular calcification in model animals of renal failure, but the association between hypozincemia and aortic stenosis (AS) prevalence in patients with end-stage k...

    Authors: Satoshi Matsui, Tomonaga Ameku, Daisuke Takada and Shinji Ono

    Citation: Renal Replacement Therapy 2020 6:49

    Content type: Research

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  29. This study aimed to evaluate cytokine levels in plasma samples over time from living-donor renal transplant recipients with no evidence of pathological and clinical rejection at least 1 year post-procedure.

    Authors: Ayato Ito, Jun Sugimura, Tomohiko Matsuura, Takaya Abe and Wataru Obara

    Citation: Renal Replacement Therapy 2020 6:48

    Content type: Research

    Published on:

  30. Pregnancy in dialysis patients is rare but challenging both for nephrologists and obstetricians. Although intensified hemodialysis is effective to achieve favorable clinical outcomes in this clinical setting, ...

    Authors: Hiroyuki Arai, Keita P. Mori, Hideki Yokoi, Ken Mizuta, Jumpei Ogura, Ko Suginami, Tomomi Endo, Yoshihiro Ikeda, Takeshi Matsubara, Tatsuo Tsukamoto and Motoko Yanagita

    Citation: Renal Replacement Therapy 2020 6:47

    Content type: Case Report

    Published on:

  31. Senior–Løken syndrome (SLS) and Bardet–Biedl syndrome (BBS) are ciliopathies. SLS is characterized by retinitis pigmentosa (RP) and familial nephronophthisis, leading to end-stage kidney disease, while BBS is ...

    Authors: Yuko Fujii, Hideki Matsumura, Akihiko Shirasu, Hyogo Nakakura, Satoshi Yamazaki, Naoya Morisada, Kazumoto Iijima and Akira Ashida

    Citation: Renal Replacement Therapy 2020 6:46

    Content type: Case Report

    Published on:

  32. It has been difficult to sufficiently achieve body-fluid management using blood volume (BV) monitor during hemodialysis (HD) with constant ultrafiltration (UF) rate. Recently, a relative BV change-guided UF co...

    Authors: Susumu Ookawara, Kiyonori Ito, Takayuki Uchida, Keito Tokuyama, Satoshi Kiryu, Takeshi Suganuma, Kyoko Hojyo, Haruhisa Miyazawa, Yuichiro Ueda, Chiharu Ito, Osamu Iimura, Kunihiko Yoshiya, Yoshiyuki Morishita, Norio Hanafusa and Kaoru Tabei

    Citation: Renal Replacement Therapy 2020 6:45

    Content type: Research

    Published on:

  33. Systemic scleroderma (SSc) involves multiple organs including the skin, the lung, the kidney, and the esophagus. Nowadays, patient life prognosis has substantially improved due to more appropriate management o...

    Authors: Takashi Ishide, Hiroshi Nishi, Hiroko Ambe, Kenjiro Honda, Motonobu Nakamura, Jiro Sato, Kota Yamamoto, Masaaki Sato and Masaomi Nangaku

    Citation: Renal Replacement Therapy 2020 6:44

    Content type: Case Report

    Published on:

  34. Pemetrexed (PEM) is administered over a long term to patients with non-squamous cell lung cancer as a maintenance therapy after platinum combination induction chemotherapy. Although decreased renal function ow...

    Authors: Kengo Umehara, Kaori Yama, Nozomi Koike, Shintarou Takayama, Azusa Wakamoto, Tae Hatuyama, Michiya Kobayashi and Hideki Sato

    Citation: Renal Replacement Therapy 2020 6:43

    Content type: Research

    Published on:

  35. The annual survey of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) was sent to 4458 dialysis facilities at the end of 2018; among these facilities, 4402 facilities (98.7%) responded to t...

    Authors: Kosaku Nitta, Shunsuke Goto, Ikuto Masakane, Norio Hanafusa, Masatomo Taniguchi, Takeshi Hasegawa, Shigeru Nakai, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Masanori Abe, Keiichi Yamamoto and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2020 6:41

    Content type: Position statement

    Published on:

  36. Multiple factors including older age, comorbidities, inflammation, metabolic acidosis, dialysis-related hypercatabolism and anabolic resistance of skeletal muscle, extraction of circulating amino acids through...

    Authors: Ryota Matsuzawa, Shohei Yamamoto, Yuta Suzuki, Yoshifumi Abe, Manae Harada, Takahiro Shimoda, Keigo Imamura, Sachi Yamabe, Haruka Ito, Shun Yoshikoshi and Atsuhiko Matsunaga

    Citation: Renal Replacement Therapy 2020 6:40

    Content type: Research

    Published on:

  37. Protein-energy wasting (PEW) is a frequently observed complication that leads to increased mortality in hemodialysis patients. However, a multifaceted assessment of PEW by combined objective nutritional parame...

    Authors: Shunsuke Yamada, Toshiaki Nakano, Shoji Tsuneyoshi, Hokuto Arase, Sho Shimamoto, Masatomo Taniguchi, Masanori Tokumoto, Hideki Hirakata, Hiroaki Ooboshi, Kazuhiko Tsuruya and Takanari Kitazono

    Citation: Renal Replacement Therapy 2020 6:39

    Content type: Research

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  38. Traditional vascular risk factors such as hypertension, diabetes mellitus, hyperlipidemia, cigarette smoking, and cardiovascular disease with myocardial infarction and atrial fibrillation have been linked to c...

    Authors: Yuta Noguchi, Marina Ito, Mai Mushika, Takuya Ito and Naoto Kawamura

    Citation: Renal Replacement Therapy 2020 6:38

    Content type: Research

    Published on:

  39. Dialysis membranes that release nitric oxide (NO) from their surface, mimicking one of the functions of endothelial cells, may suppress platelet reactivity during hemodialysis treatment. The aim of the present...

    Authors: Shunichiro Urabe, Kenichi Kokubo, Hiroshi Tsukao, Kozue Kobayashi, Minoru Hirose and Hirosuke Kobayashi

    Citation: Renal Replacement Therapy 2020 6:37

    Content type: Research

    Published on:

  40. Social frailty—the lack of a connection to society and infrequent social activities—has been reported to be associated with future declines in physical function in elderly individuals. This study aimed to eval...

    Authors: Koki Abe, Yoshinosuke Shimamura, Takuto Maeda, Yoshikazu Kato, Yasuyoshi Yoshimura, Tomomi Tanaka and Hideki Takizawa

    Citation: Renal Replacement Therapy 2020 6:36

    Content type: Research

    Published on:

  41. Polysulfone (PS) dialyzers are most frequently used worldwide for chronic renal failure patients and they are produced by several manufacturers. Despite using the same materials, differences in biocompatibilit...

    Authors: Mitsuru Kubo, Ryoichi Nakazawa, Kazuhiro Akiyama, Yoshiho Tsunoda, Kazumasa Kimura, Kenji Koide, Yasuhisa Matsushima, Shinji Hasegawa, Koichi Ikeda and Nakanobu Azuma

    Citation: Renal Replacement Therapy 2020 6:35

    Content type: Research

    Published on:

  42. Septic shock is a life-threatening condition and one of the most common causes of acute kidney injury (AKI). The acrylonitrile-co-methallyl sulfonate surface-treated (AN69ST) membrane used in severe sepsis was...

    Authors: Naoto Nishizaki, Riko Ueno, Yuki Nagayama, Hanako Abe, Akina Matsuda, Akira Mizutani, Kaoru Obinata, Tadaharu Okazaki and Toshiaki Shimizu

    Citation: Renal Replacement Therapy 2020 6:34

    Content type: Case Report

    Published on:

  43. To our knowledge, there are no preexisting reports concerning rilpivirine (RPV) removal by hemodialysis and peritoneal dialysis.

    Authors: Nanako Oshiro, Kentaro Kohagura, Shoji Tsuneyoshi, Masao Tateyama, Ryo Zamami, Hitoshi Uehara, Jiro Fujita and Yusuke Ohya

    Citation: Renal Replacement Therapy 2020 6:33

    Content type: Case Report

    Published on:

  44. Brain natriuretic peptide (BNP) levels are used as a marker of heart failure, which is the leading cause of morbidity and mortality in dialysis patients. BNP levels increase as renal function declines. The ran...

    Authors: Etsuko Kumagai, Keiko Hosohata, Kazuhiro Furumachi and Shinji Takai

    Citation: Renal Replacement Therapy 2020 6:32

    Content type: Research

    Published on:

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